Quantifying Stranded Implant Displacement Following Prostate Brachytherapy

نویسندگان

  • Julio Lobo
  • Mehdi Moradi
  • Nick Chng
  • Ehsan Dehghan
  • Gabor Fichtinger
  • William J. Morris
  • Septimiu E. Salcudean
چکیده

We aim to compute radioactive stranded-implant displacement during and after prostate brachytherapy. We present the methods used to identify corresponding seeds in planned, intra-operative and postimplant patient data that enable us to compute seed displacements. A minimum cost network flow algorithm is used, on 8 patients, for needle track detection to group seeds into needles that can be matched between datasets. An iterative best line detection algorithm is used both to help with needle detection and to register the different datasets. Our results show that there was an average seed misplacement of 5.08 +/- 2.35 mm during the procedure, which then moved another 3.10 +/- 1.91 mm by the time the quality assurance CT was taken. Several directional trends in different regions of the prostate were noted and commented on.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Evaluation of the dosimetric impact of loss and displacement of seeds in prostate low-dose-rate brachytherapy

PURPOSE To analyze the seed loss and displacement and their dosimetric impact in prostate low-dose-rate (LDR) brachytherapy while utilizing the combination of loose and stranded seeds. MATERIAL AND METHODS Two hundred and seventeen prostate cancer patients have been treated with LDR brachytherapy. Loose seeds were implanted in the prostate center and stranded seeds in the periphery of the gla...

متن کامل

Quantifying Iodine-125 Placement Accuracy In Prostate Brachytherapy Using Post-Implant Transrectal Ultrasound Images

PURPOSE: The quality of a prostate brachytherapy implant depends on the accurate placement of sources. This study quantifies the misplacement of iodine-125 sources from the intended location using intra-operative ultrasound images. METHOD AND MATERIALS Iodine-125 sources were manually identified in the post-implant ultrasound images and compared to the pre-operative plan. Due to the subjective ...

متن کامل

Radioactive seed migration after prostate brachytherapy with iodine-125 using loose seeds versus stranded seeds.

OBJECTIVES To assess the incidence and clinical parameters that could influence migration of seeds in localized prostate cancer patients treated by stranded versus loose sources by Iodine-125 brachytherapy. MATERIALS AND METHODS 100 patients were treated from January/1998 until December/2006. Age, PSA, clinical stage, Gleason, prostate volume, number of seeds, activity of radioactive seeds, a...

متن کامل

Evaluation of the effect of prostate volume change on tumor control probability in LDR brachytherapy

PURPOSE This study evaluates low dose-rate brachytherapy (LDR) prostate plans to determine the biological effect of dose degradation due to prostate volume changes. MATERIAL AND METHODS In this study, 39 patients were evaluated. Pre-implant prostate volume was determined using ultrasound. These images were used with the treatment planning system (Nucletron Spot Pro 3.1(®)) to create treatment...

متن کامل

Radiation-Induced Soft Tissue Sarcoma after Prostate Brachytherapy

Secondary malignancy arising following brachytherapy for prostate cancer is rare in medical literature. We present a case of post-brachytherapy soft tissue sarcoma in the pelvis approximately 7 years after 103-P permanent seed implant. The patient developed a large left pelvic mass associated with significant left leg pain. He was not a good candidate for radical surgery, chemotherapy, or re-ir...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention

دوره 14 Pt 1  شماره 

صفحات  -

تاریخ انتشار 2011